LC/MS分析血清中小分子样品净化方法
前言:
The removal of matrix interferants from biological samples using off-line SPE adds a time-consuming step to analytical separations. On-line sample clean-up utilizing SEC minimizes the number of steps, minimizes the total time required for analysis and has the added advantage that it can be automated.
结论:
• This poster successfully demonstrates the use of on-line SEC for the extraction of analytes from serum.
• On-line SEC analysis provides a suitable alternative to off-line SPE for the clean-up of samples in biological matrices.
• The methodology is robust and reproducible.
• Unlike off-line SPE, the process can be automated
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