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Extraction of Ancient DNA

关键词: extraction ancient dna来源: 互联网

The DNA extraction process represents one of the critical stages in the analysis of degraded or ancient DNA. If polymerase chain reaction (PCR) amplification starts from a poor extract containing low template quantities, stochastic variation in the amplification of individual alleles may lead to allelic dropout (1 ), resulting in a high risk of false-homozygous typing of a heterozygous sample (2 ).

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