Construction of Human Naive Antibody Gene Libraries
Human antibodies are valuable tools for proteome research and diagnostics. Furthermore, antibodies are a rapidly growing class of therapeutic agents, mainly for inflammation and cancer therapy. The first therapeutic antibodies are of murine origin and were chimerized or humanized. The later-developed antibodies are fully human antibodies. Here, two technologies are competing the hybridoma technology using transgenic mice with human antibody gene loci and antibody phage display. The starting point for the selection of human antibodies against any target is the construction of an antibody phage display gene library. In this review we describe the construction of human naive and immune antibody gene libraries for antibody phage display.
- 人α/β干扰素受体(IFN-α/βR)酶联免疫分析(ELISA)
- 人补体片段C5a(C5a)ELISA试剂盒 说明书
- 人降钙素基因相关肽(CGRP)ELISA试剂盒 说明书
- 人血管内皮抑素(Endostatin)ELISA试剂盒 说明书
- ELISA各环节中常见问题及解决方法
- Staining for total receptors
- Selection of VHH Antibody Fragments That Recognize Different A Depositions Using Complex Immune Libraries
- Rapid Methods for Testing Inhibitors of Mycobacterial Growth
- Implementing the Modular MHC Model for Predicting Peptide Binding
- Expression of Antibody Fragments in Transgenic Plants