CD65/CD65s分子
CD65/CD65s 分子 CD65 常用单克隆抗体或代号: VIM2,HE10,CF4 主要表达细胞: PMN [M] 分子质量(kDa)和结构: 岩藻糖基神经节苷脂 功 能: 中性粒细胞活化 CD65s 常用单克隆抗体或代号: 88H7 主要表达细胞: PMN,M [M] 分子质量(kDa)和结构: Siapoly- sialyl- n- acetylactosamide 功 能:与吞噬作用有关 CD65 Aka VIM2, ceramide-dodecasaccharide Adhesive molecule that appears to be significant risk factor for extravascular AML infiltration Positive staining (normal): myeloid cells, monocytes CD65s Widely used for acute leukemia cell typing and to identify a subset of pre-pre-B ALL Aka sialylated-CD65 May inhibit phagocytosis Positive staining (normal): granulocytes, monocytes Positive staining (disease): myeloid leukemia cells