p53 Signaling Pathway PCR Array

p53信号通路PCR基因芯片
 

Product	Species	Technology	Cat. No.
p53 Signaling Pathway PCR Array	Human	Gene Expression	PAHS-027Z
p53 Signaling Pathway PCR Array	Mouse	Gene Expression	PAMM-027Z
p53 Signaling Pathway PCR Array	Rat	Gene Expression	PARN-027Z

p53 Signaling Pathway RT² Profiler™ PCR Array profiles the expression of 84 genes related to p53-mediated signal transduction. The array includes p53-related genes involved in the processes of apoptosis, the cell cycle, cell growth, proliferation, and differentiation, and DNA repair. Using real-time PCR, you can easily and reliably analyze expression of a focused panel of genes related to p53 signaling pathway with this array.
p53信号通路PCR基因芯片可以同时检测84个与p53信号通路相关的基因。这些基因包括参与细胞凋亡、细胞周期、细胞生长、增殖和分化以及DNA修复等过程的p53相关基因。利用实时定量PCR，研究者可以方便并且可信地对与p53信号通路相关的基因进行同时检测。
p53 Activation:ATM, ATR, BBC3, BRCA1, CDKN1A (p21CIP1/WAF1), CDKN2A (p16INK4), CHEK1, CHEK2 (RAD53), FOXO3, GML, MDM2, MSH2, SIRT1, TP63, TP73.
p53 Regulators & Interactors:CDKN2A (p16INK4), DNMT1, HDAC1, KAT2B, MDM2, MDM4, SIRT1, TADA3, TP53AIP1, TP53BP2, TP63 (TP73L), TP73.
Target Genes:
Apoptosis:APAF1, BAX, BBC3, BTG2, CASP9, EGFR, EI24, ESR1 (ERa), FAS (TNFRSF6), PRKCA, TNF, TNFRSF10B (DR5), TP53, TP53AIP1, TP73.
Cell Cycle: CCNG1, CDC25A, CDC25C, CDKN1A (p21CIP1/WAF1), E2F1, E2F3, GML, MDM2, MYC, PPM1D, RB1, RPRM, SESN2, SIAH1.
DNA Repair:BRCA1, BTG2, EGFR, GADD45A, PCNA, PTTG1.
Angiogenesis:BAI1, IL6, PTEN.
Downstream Responses:
Apoptosis:APAF1, BCL2, BCL2A1, BID, BIRC5, CASP2, CASP9, CRADD, FADD, FASLG (TNFSF6), IGF1R, MCL1, NF1, NFKB1, PIDD (LRDD), RELA, TNFRSF10D, TRAF2, WT1.
Cell Cycle:CCNB1, CCNE1, CCNG1, CCNH, CDK1 (CDC2), CDK4, PRC1, TSC1.
DNA Repair:BRCA2, MLH1, XRCC5.
Transcription Factors & Regulators:BRCA2, EGR1, JUN, MYOD1, NFKB1, RELA, STAT1.
Other Genes:HK2, KRAS.